This simple blood test measures how much oestradiol is the blood. Oestradiol is also often called E2 and is one of four different types of hormone that are produced by the ovaries. The placenta the adrenal glands, the testes, and some tissues will also produce a very small amount of oestradiol.
Maintaining the right level of oestrogen is vital for the reproductive health of an individual. If there is too little or excessive oestrogen this might give rise to medical problems, UTI’s and loss of bone strength. It might also lead to depression. Often if a doctor is concerned about puberty issues, fertility or if a patient is menopausal this test will be ordered. Here are some explanations as to why this test might be asked for, how it is performed and what the results might indicate.
An Oestradiol test can help with the diagnosis of various hormonal issues relating to fertility puberty and menopause related concerns.
Although oestrogen is referred to as a female sex hormone, it is also vital in male development and growth and fluctuating levels might affect how the body grows or how it works.
Oestradiol levels affect the development and the function of the reproductive system. If levels are too high or too low and the organs affected may be:
The fallopian tubes
The breast tissue
The patient’s libido
Contribute to erectile dysfunction
The development of sperm cells
During the years when women are fertile, oestradiol production will be at its height. After a woman reaches menopause, oestradiol levels will drop.
Problems that might be caused by abnormal levels of oestradiol include:
Problems with menstruation with menopause symptoms
Problems with conception and fertility
Gynaecomastia or benign swellings in breast tissue, in men
Tumour development in the ovaries
Cancer of the breast
An oestradiol test can be used to assess puberty if a child seems to be entering puberty earlier or later.
Women undergoing gender reassignment might be prescribed oestradiol as an element of the hormone therapy hormone therapy required to develop more feminine characteristics. Doctors will test oestradiol levels regularly in this case.
This is a simple blood test, and as such the risk is low. Any test however, that involves a needle will carry some risks, for example:
Some bruising at the site
The feeling of dizziness, light-headedness, or even a faint
Some soreness or pain at the site of the blood taking
Possible there may be more than one puncture if the phlebotomist has had trouble finding a vein
A build-up of blood under the skin
Taking birth control medication might have an impact on oestradiol test results
For some blood tests fasting is recommended but this is not the case with an oestradiol test.
If birth control or hormonal therapy medication is being taken then you should inform your medical professional before the test as some medication might influence the test results.
An oestradiol test involves taking a blood sample from the arm or the hand. The area will be cleaned and a suitable vein located.
They will use a needle to draw blood from the area, which they will then be sent to a laboratory for testing.
Oestradiol test results will show various things depending on the sex the age or the health history of the person being tested.
Oestradiol levels are measured as pg/ml (picograms per millilitre)
Premenopausal females – normal range 30 to 400 pg/ml.
Postmenopausal females – normal range 0 to 30 pg/ml.
Males patients – normal range 10 to 50 pg/ml.
Low oestradiol levels may indicate
onset of the menopause
rapid weight loss leading to low readings
pituitary hormone level is low
a pregnancy that is failing
a chromosomal condition, Turner syndrome, that can give rise to infertility
If high Oestradiol levels are recorded, this could indicate:
The patient is suffering from liver damage
The patient is hyperthyroid
Tumours in the testicles
Tumours in the adrenal glands
The presence of a pregnancy as well as the menstrual cycle of a patient can alter results as follows:
·Oestradiol levels will be higher in pregnancy because oestradiol is produced by the placenta.
Oestradiol levels are raised at the time of ovulation but low during menstruation
High levels of oestradiol in adolescents could point, in the case of girls, to early puberty or conversely, in boys, to a delayed puberty.
Blood London have been providing Oestradiol (E2) Blood Test UK on a self-referral basis to patients in Central and Greater London for over 20 years. Simply walk-in weekdays between 9am and 6pm or on weekends between 10am and 2pm, to have your blood taken by a highly experienced professional in our private, Harley Street clinic using some of the best labs in europe.
Please note that when ordering blood tests on a self-request basis, we will forward you the laboratory report without note or comment from our doctors unless you are under their care.
Following the results of your test, if you would like to undergo a consultation, further testing or treatment please feel free to reach out to the clinic and we'll be happy to help.
Select the test that you would like to undergo
Go to the Harley Street clinic for your blood draw and pay for your test in person
As soon as the results are ready, the will be sent to you by your chosen method